We are pleased to announce the eighth release of WormBase ParaSite.
We now have a total of 131 genomes representing 112 species. New species in this release are Globodera rostochiensis (PRJEB13504) and Gyrodactylus salaris (PRJNA244375). A new higher-quality assembly is also available for Heligmosomoides polygyrus (PRJEB15396).
Our assembly quality widgets has been updated with new BUSCO scores. We have used BUSCO v2 and either the lineage Nematoda (for nematodes) or Metazoa (for platyhelminthes) to calculate more accurate scores.
Up to 3 awards will be made for early-career researchers from Africa, Asia and Latin America to support participation at the meeting; the bursaries will cover registration fees (GBP 495, approx USD 625), and a sum of USD 1000 towards airfare and ground transportation costs. Awardees will be selected on the basis of Abstracts submitted to the conference, and a letter of application outlining the reasons for attending the meeting. Applicants should register through this website and send their application letter to Hydra@ed.ac.uk before the closing date of 31 March 2017.
Conference website: http://hydra.bio.ed.ac.uk/
Registration is now open for the British Society for Parasitology Spring Meeting, to be held in Dundee from 2nd April to 5th April 2017.
WormBase ParaSite will be present throughout the conference, including a workshop session. We will also be available to answer questions and provide practical demonstrations. More details will follow.
Abstract submission deadlines:
Oral presentation – 19th February 2017
Poster – 5th March 2017
More details and registration for the conference: http://bsp.uk.net/2016/10/04/bsp-spring-meeting-2017/
We look forward to seeing you in Dundee!
Monday 12 – Tuesday 13 June 2017
The Royal Society at Chicheley Hall, home of the Kavli Royal Society International Centre
Organised by Dr Rachel McMullan and Cecile Sarabian
I am organising an exciting 2-day, residential-style meeting at Royal Society Chicheley Hall on 12-13 June 2017 entitled, Evolution of pathogen and parasite avoidance behaviours.
This meeting will bring together a multidisciplinary group of scientists in the field of pathogen and parasite avoidance, such as invertebrates, vertebrates and humans. Further information can be found here: https://royalsociety.org/science-events-and-lectures/2017/06/evolution-pathogen-parasite/
The meeting is free to attend; participants just have to cover their accommodation, travel and subsistence. Please let me know if you need more information.
We would like to point you to
Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers. by McNutty SN, et al. published in PLOS Genetics.
It not only describes the genome of Fasciola hepatica, as can be seen on WormBase ParaSite, but also describes the first observation of endobacteria in this species.
We would like to draw your attention to the paper Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings. by Megan Cross, et al.
As trehalose is an essential disaccharide for many pathogens (including parasites) but is neither required nor synthesized by mammalian cells, the biosynthetic pathway of trehalose thus constitutes a candidate target for chemotherapeutic intervention.
There is also an overview of The role of trehalose in the physiology of nematodes by Behm CA in 1997, which might be of interest as it explains the underlying pathway.
The phylogeny can be also easily seen on the comparative gene tree of the B.malayi gene.
Registration remains open for the “Molecular Helminthology: An Integrated Approach” conference, which will be held from 19th to 22nd March 2017 at the Hyannis Resort and Conference Center, Cape Cod, MA, USA.
Late abstract submissions are accepted until 31st January 2017.
WormBase ParaSite will be hosting a workshop at this meeting. Join us between 10:00 and 10:45 on Monday 20th March to learn more about WormBase ParaSite.
Further details and registration: http://www.molecular-helminthology-conference.com/
The publication “The genome of Onchocerca volvulus, agent of river blindness” by James A Cotton, et. al describes in detail the O. volvulus genome available at WormBase and ParaSite.
It includes a section on gene family evolution of O. volvulus and relatives showing the phylogeny of 9 selected nematodes covering 3 clades. In addition it describes potential drug targets based on their predicted metabolic pathway in relation to their druggability by known compounds, which could be expanded to other organisms.
This paper can be also cited as reference for the genome assemblies.